ABCA1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ABCA1 |
| Clone | [AB.H10] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 100ug/100ul |
| Applications | Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognize specifically ABCA1 from human, mouse, and chicken. Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. |
| Immunogen | Immunogen: Peptides amino acids 1800-2260 (C-Terminal end) |
| Other Names | [ATP-binding cassette sub-family A member 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter A1; cholesterol efflux regulatory protein; membrane-bound; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; Cholesterol efflux regulatory protein], [ABCA1; ABCA1; TGD; ABC1; CERP; ABC-1; HDLDT1] |
| Gene, Accession # | [ABCA1], Gene ID: 19, NCBI: NP_005493.2 |
| Catalog # | MBS415413 |
| Price | $255 |
| Order / More Info | ABCA1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Umeda, T et al. Regulation of cholesterol efflux by amyloid beta secretion. J. Neurosci. Res. 88:1985-94 (2010). PubMed: 20155813. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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