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Antigenic Specificity | CTCF - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been a |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CTCF |
Other Names | [transcriptional repressor CTCF isoform 2; Transcriptional repressor CTCF; transcriptional repressor CTCF; CCCTC-binding factor; 11-zinc finger protein; CCCTC-binding factor; CTCFL paralog] |
Gene, Accession # | [CTCF], Gene ID: 10664, NCBI: NP_001177951.1, UniProt: P49711 |
Catalog # | MBS3219698 |
Price | $335 |
Order / More Info | CTCF - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |