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Antigenic Specificity | PAFAH1B1 (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat (predicted reactivity: bovine, chicken, monkey, porcine) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PAFAH1B1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 76-110 amino acids from the N-terminal region of human PAFAH1B1. Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet- activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity). Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plu |
Immunogen | n/a |
Other Names | [Platelet-activating factor acetylhydrolase IB subunit alpha {ECO:0000255|HAMAP-Rule:MF_03141}; Lissencephaly-1 protein {ECO:0000255|HAMAP-Rule:MF_03141}; LIS-1 {ECO:0000255|HAMAP-Rule:MF_03141}; PAF acetylhydrolase 45 kDa subunit {ECO:0000255|HAMAP-Rule:MF_03141}; PAF-AH 45 kDa subunit {ECO:0000255|HAMAP-Rule:MF_03141}; PAF-AH alpha {ECO:0000255|HAMAP-Rule:MF_03141}; PAFAH alpha {ECO:0000255|HAMAP-Rule:MF_03141}; PAFAH1B1 {ECO:0000255|HAMAP-Rule:MF_03141}] |
Gene, Accession # | [PAFAH1B1], Gene ID: 5048, NCBI: NP_000421.1, UniProt: P43034 |
Catalog # | MBS9205460 |
Price | $165, $370 |
Order / More Info | PAFAH1B1 (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Reiner O.,et al.Nature 364:717-721(1993). Lo Nigro C.,et al.Hum. Mol. Genet. 6:157-164(1997). Zhao M.J.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases. Feng Z.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). |