Human PD-1/CD279, 7G12, Tracer ( Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human PD-1/CD279, 7G12, Tracer ( |
| Clone | [7G12] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1,k |
| Format | biotin conjugate |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reactive with recombinant human programmed cell death-1 (PD-1). Reactivity with natural PD-1 has not been evaluated. Programmed Cell Death-1 (PD-1), also called CD279, is a 288 amino acid cell surface protein that belongs to the immunoglobulin superfamily. The protein is expressed on T cells, B cells and macrophages. When PD-1 is joined with its ligand (CD274 or B7-H1), the immune cell's activation and effector function are attenuated. Research suggested that PD1 pathway is mainly involved with attenuation at periphery sites while the B7/CTLA-4 pathway is primarily involved with the attenuation of the activation of immune cells in secondary lymphoid organs. PD-1 pathway is implicated with cancer's immune-evasion, autoimmunity, and Listeria |
| Immunogen | Immunogen: Human cell expressed recombinant programmed cell death-1 (Pro21-Gln162 with a histidine tag at C-terminus). Accession No.: NP-005009.2. In addition to the immunogen, the antibody also reacts with another human cell expressed recombinant PD-1 (Leu25-Gln167 with an Fc tag at C-terminus). Accession No.: Q15116. Light Chain: Kappa. Fusion Myeloma: Sp2/0-Ag14. Target Protein: Human programmed cell death-1 (PD-1) |
| Other Names | [mAb Human programmed cell death-2; Mouse to human programmed cell death-1 (PD-1); mouse mAb to human CD279, Tracer (Biotin Labeled), Clone 7G12; Biotin conjugated Mouse (mAb) to human programmed cell death-1 (PD-1)], [PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1] |
| Gene, Accession # | [PD-1/CD279], Gene ID: 5133, NCBI: NP_005009.2, UniProt: Q15116 |
| Catalog # | MBS590084 |
| Price | $520 |
| Order / More Info | Human PD-1/CD279, 7G12, Tracer ( Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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