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Antigenic Specificity | Caspase-9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, Gerbil, human, mouse, rat |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFalpha, T |
Immunogen | Immunogen Information: A recombinant catalytically active of human Caspase-9 protein was used as the immunogen for this antibody |
Other Names | [CASP9; MCH6; Apoptotic protease Mch-6; APAF-3; Apoptotic protease-activating factor 3; ICE-LAP6; ICE-like apoptotic protease 6; to Caspase-9; Caspase-9; Caspase-9], [CASP9; CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; MCH6; CASP-9; APAF-3; ICE-LAP6] |
Gene, Accession # | [CASP9], Gene ID: 842, NCBI: P55211.3, UniProt: P55211 |
Catalog # | MBS668577 |
Price | $270 |
Order / More Info | Caspase-9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |