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Antigenic Specificity | ING3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Eaf4; ING2; MEAF4; p47ING3] |
Gene, Accession # | [ING3], Gene ID: 54556, NCBI: Q9NXR8.2, UniProt: Q9NXR8 |
Catalog # | MBS9126183 |
Price | $200, $275, $430 |
Order / More Info | ING3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |