Mouse CD3e-BIMA Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD3e-BIMA |
| Clone | [145-2C11] |
| Host Species | Hamster |
| Reactive Species | mouse |
| Isotype | IgG kappa |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Identification and enumeration of CD3+ cells by Flow Cytometry, Immunoprecipitation, Western Blot, In vitro depletion of CD3+ cells, In vitro activation of T cells, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Mouse CD3epsilon (Mr 25 kDa). CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naive T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific t |
| Immunogen | Immunogen: H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37. Characterization: To insure acceptable performance, each batch of product is tested by flow cytometry to conform to the characteristics of a standard reference. Representative data are included in this product insert. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS670344 |
| Price | $280 |
| Order / More Info | Mouse CD3e-BIMA Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Leo, O., M. Foo, D. Sachs, L. Samuelson, and J. Bluestone. 1987. Proc. Natl. Acad. Sci. USA 84:1374.2. Portoles, P., J. Rojo, A. Golby, M. Bonneville, S. Gromkowski, L. Greenbaum, C. A. Janeway, Jr., D. B. Murphy, and K. Bottomly. 1989. J. Immunol. 142:4169.3. Kruisbeek, A.M., and E. Shevach. 1991. In: Currents Protocols in Immunology. J. Coligan, A. Kruisbeek, D. Margulies, E.M. Shevach, and W. Strober, eds. John Wiley & Sons, New York, pp. 3.12.1-3.12.14.4. Duke, R.C., J.J. Cohen, S.A. Boehme, M.J. Lenardo, C.D. Surh, H. Kishimoto, and J. Sprent. 1995. In: Currents Protocols in Immunology. J. Coligan, A. Kruisbeek, D. Margulies, E.M. Shevach, and W. Strober, eds. John Wiley & Sons, New York, pp. 3.17.1-3.17.33.5. Ucker, D.S., J. Meyers, and P.D. Obermiller. 1992. J. Immunol. 149:1583.6. Wang, R., K.M. Murphy, D.Y. Loh, C. Weaver, and J.H. Russell. 1993. J. Immunol. 150:3832.7. Salvadori, S., B. Gansbacher, A.M. Pizzimenti, and K.S. Zier. 1994. J. Immunol. 153.5176.8. Payer, E., A. Elbe, and G. Stingl., 1991. J. Immunol. 146:2536. |
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MYBIOSOURCE INC.
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