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Antigenic Specificity | BAGE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 0.6mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2(B melanoma antigen 2), also known as Cancer/testis antigen 2.2, is 109 amino acid secreted proteins that is expressed in 22% of melanomas, lung and bladder carcinomas, and is also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues o |
Immunogen | Immunogen: Synthetic peptide of human BAGE2 |
Other Names | [B melanoma antigen 2; B melanoma antigen family, member 2; Cancer/testis antigen 2.2; CT2.2] |
Gene, Accession # | [BAGE2], NCBI: Q86Y30.1, UniProt: Q86Y30 |
Catalog # | MBS2561499 |
Price | $110, $150, $225 |
Order / More Info | BAGE2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |