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Antigenic Specificity | CENP-A |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot (IB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human CENP-A. Reactivity with other species has not been investigated. Replicated chromosomes include two kinetochores that control chromosome segregation during mitosis. Centromere Protein-A (CENP-A), a histone H3-like protein, contains a C-terminal H3-like domain which is required for centromere localization of CENP-A. It is essential for kinetochore targeting of CENP-C. In the presence of DNA, CENP-A forms an octameric complex with histones H2A, H2B, and H4. CENP-A specifically localizes to active centromeres and is a component of specialized centromeric nucleosomes on which kinetochores are assembled. CENP-A is essential for nucleosomal packaging of centromeric DNA at interphase and functions as a centromere for |
Immunogen | Antigen: Synthetic peptide corresponding to a sequence within human CENP-A. |
Other Names | [CENP-A], [HAN_3g422] |
Gene, Accession # | [CENP-A], NCBI: ABW98231.1 |
Catalog # | MBS190673 |
Price | $335 |
Order / More Info | CENP-A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |