RIN1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RIN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RIN1 antibody detects endogenous levels of total RIN1. Function: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.Subunit Structure: Interacts with the GTP-bound form of Ras proteins (NRAS, HRAS and KRAS). This interaction prevents the association between RAF1 |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasmic and Plasma Membrane Tissue Specificity: Expressed in all tissues examined with high levels in brain, placenta and pancreas. Predicted Cross Reactivity: Pig, Horse, Dog Similarity: Pig (80%), Horse (90%), Dog (90%) |
| Other Names | [Ras and Rab interactor 1; ras inhibitor 1; ras inhibitor; Ras inhibitor JC99; ras inhibitor RIN1; Ras interaction/interference protein 1; RIN 1] |
| Gene, Accession # | [RIN1], Gene ID: 9610, NCBI: NP_004283.2, UniProt: Q13671 |
| Catalog # | MBS9605838 |
| Price | $240, $280 |
| Order / More Info | RIN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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