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Antigenic Specificity | DDX20 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DDX20 antibody detects endogenous levels of total DDX20. Function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from t |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Nucleus > Gem. Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (89%), Bovine (100%), Horse (89%), Sheep (100%), Rabbit (89%), Dog (89%), Chicken (100%) |
Other Names | [Component of gems 3; DDX 20; ddx20; DDX20_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD box protein DP103; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 103kD; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20; DEAD/H BOX 20; DKFZP434H052; DP 103; DP103; Gemin-3; Gemin3; Probable ATP dependent RNA helicase DDX20; Probable ATP-dependent RNA helicase ddx20; SMN interacting protein] |
Gene, Accession # | [DDX20], Gene ID: 11218, NCBI: NP_009135.4, UniProt: Q9UHI6 |
Catalog # | MBS9605786 |
Price | $240, $280 |
Order / More Info | DDX20 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |