USP36 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | USP36 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: USP36 antibody detects endogenous levels of total USP36. Function: Deubiquitinase essential for the regulation of nucleolar structure and function. Required for cell and organism viability. Plays an important role in ribosomal RNA processing and protein synthesis, which is mediated, at least in part, through deubiquitination of DHX33, NPM1 and FBL, regulating their protein stability (PubMed:29273634, PubMed:19208757, PubMed:22902402). Function as a transcriptional repressor by deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, such as CDKN1A, thereby preventing histone H3 'Lys-4' trimethylation (H3K4) (PubMed:29274341). Specifically deubiquitinates MYC in the nucleolus, leading to prevent |
| Immunogen | Immunogen: A synthesized peptide derived from human USP36 Subcellular Location: Nucleus > Nucleolus. Tissue Specificity: Broadly expressed. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus Similarity: Pig (92%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Chicken (100%), Xenopus (92%) |
| Other Names | [Deubiquitinating enzyme 1; Deubiquitinating enzyme 36; DUB1; FLJ12851; KIAA1453; Ubiquitin carboxyl-terminal hydrolase 36; Ubiquitin specific peptidase 36; Ubiquitin specific processing protease 36; Ubiquitin thioesterase 36; Ubiquitin thiolesterase 36; Ubiquitin-specific-processing protease 36; UBP36_HUMAN; Usp36] |
| Gene, Accession # | [USP36], Gene ID: 57602, NCBI: NP_001308220.1, UniProt: Q9P275 |
| Catalog # | MBS9602266 |
| Price | $240, $280 |
| Order / More Info | USP36 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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