Human CD279 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD279 antibody, protein, ELISA kits.
| Edit | |
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| Antigenic Specificity | Human CD279 |
| Clone | [J116] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. |
| Immunogen | n/a |
| Other Names | [PD-1; Programmed Death-1] |
| Gene, Accession # | [CD279], Gene ID: 5133, NCBI: Q15116.3, UniProt: Q15116 |
| Catalog # | MBS2556965 |
| Price | $85, $100 |
| Order / More Info | Human CD279 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Francisco LM, Sage PT, and Sharpe AH. 2010. Immunological Rev. 236:219. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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