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Antigenic Specificity | AIF (IN) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-AIF (IN) [Rabbit antibody to peptide corresponding to aa 517-531 of human AIF. Recognizes human, mouse, and rat AIF.]. This antibody recognizes human, mouse, and rat AIF (67 kD). Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of caspases, caspase-activated DNase, and several other proteins. A novel protein that causes chromatin condensation and DNA fragmentation has been designated Apoptosis Inducing Factor (AIF). AIF localizes in mitochondria and translocates to the nucleus when apoptosis is induced. This event is followed by the release of chytochrome c and caspase-9 from mitochondria. AIF is hig |
Immunogen | Antigen: Peptide corresponding to aa 517-531 of human AIF. This sequence is identical to those of mouse and rat AIF. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194020 |
Price | $415 |
Order / More Info | AIF (IN) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |