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Antigenic Specificity | MAPK4 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.Structure: Homodimer. Heterodimer with ERK3/MAPK6. Interacts with (via FRIEDE motif) MAPKAPK5.Expression: High expression in heart and brain. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 500-550 on human Mitogen-activated protein kinase 4. Conjugation: Unconjugated |
Other Names | [Affinity Purified Mitogen-activated protein kinase 4; ERK-4; Extracellular signal-regulated kinase 4; MAP kinase 4; MAP kinase isoform p63; MAPK4; p63 MAPK; PRKM4; Protein kinase, mitogen-activated, 4; Protein-tyrosine kinase ERK3-related; RMNK2] |
Gene, Accession # | [MAPK4], Gene ID: 5596, NCBI: NP_001278968.1, UniProt: P31152 |
Catalog # | MBS5400513 |
Price | $390 |
Order / More Info | MAPK4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |