NFATC1, Human Antibody from NKMAX Co. Ltd.
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| Antigenic Specificity | NFATC1, Human |
| Clone | AT1C3 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a kappa |
| Format | Protein G purified |
| Size | 50ul, 100ul |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | ELISA, WB, ICC/IF, FACS |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATc1) is a component of the nuclear factor of activated T cells DNA-binding transcription complex which consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. This protein plays a main role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription and functions as a major molecular target for the immunosuppressive drugs such as cyclosporine A. NFATc1 is expressed in most human primary lymphocytes and mature human T- and B-cell neoplasms. |
| Immunogen | Recombinant human NFATc1 (428-716aa) purified from E. coli |
| Other Names | nuclear factor of activated T-cells, cytosolic component 1 isoform A, NF-ATC, NFATc, NFAT2 |
| Gene, Accession # | NCBI: NP_765978, UniProt: O95644 |
| Catalog # | ATGA0133 |
| Price | $170, $290 |
| Order / More Info | NFATC1, Human Antibody from NKMAX Co. Ltd. |
| Product Specific References | Vizza D, et al. Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. (PLoS One. 2013){https://pubmed.ncbi.nlm.nih.gov/24244623/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
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Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
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http://www.nkmaxbio.com
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