alpha-Smooth Muscle Actin/ACTA2, Human Antibody from NKMAX Co. Ltd.

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Antigenic Specificityalpha-Smooth Muscle Actin/ACTA2, Human
CloneAT132D3
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein A purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA, WB, ICC/IF, FACS
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DescriptionAlpha-actin-2 also known as actin, aortic smooth muscle or alpha smooth muscle actin (alpha-SMA, SMactin, alpha-SM-actin, ASMA). Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic beta- and gamma-actin proteins are referred to as non-muscle actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility. Actin has major functions. Firstly, F-actin polymers form microfilaments - polar intracellular tracks for kinesin motor proteins, allowing the transport of vesicles, organelles and other cargo. Actin is a component of the cytoskeleton and links to alpha-actinin, E-cadherin and beta-catenin at adherens junctions. actin has a role in cell motility through polymerization and depolymerization of fibrils.
ImmunogenRecombinant human ACTA2 (3-377aa) purified from E. coli
Other NamesAortic smooth muscle actin, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, Actin, Aortic smooth muscle, Intermediate form, ACTSA, ACTVS, GIG46
Gene, Accession #NCBI: NP_001604, UniProt: P62736
Catalog #ATGA0358
Price$170, $290
Order / More Infoalpha-Smooth Muscle Actin/ACTA2, Human Antibody from NKMAX Co. Ltd.
Product Specific ReferencesLiu X, et al. Human aortic valve interstitial cells obtained from patients with aortic valve stenosis are vascular endothelial growth factor receptor 2 positive and contribute to ectopic calcification. (J Pharmacol Sci . 2021){https://pubmed.ncbi.nlm.nih.gov/33451756/}
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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