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Antigenic Specificity | Crystallin alpha B/CRYAB, Human |
Clone | 2E8. |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | alpha-Crystallins are composed of two gene products; alpha-Crystallin A and B, for acidic and basic, respectively. alpha-Crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-Crystallin A and B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. alpha-Crystallin B is expressed widely in many tissues and organs and occurs in many neurological diseases. |
Immunogen | Recombinant human Crystallin alpha B (1-175 aa) purified from E. coli |
Other Names | Crya2, Crya-2, Cryab, Crystallin alpha B, Alpha-crystallin B chain, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component |
Gene, Accession # | NCBI: NP_001876.1, UniProt: P02511 |
Catalog # | ACB0617 |
Price | $170, $290 |
Order / More Info | Crystallin alpha B/CRYAB, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |