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Antigenic Specificity | 6-phosphogluconate Dehydrogenase/PGD, Human |
Clone | AT46B3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PGD (Phosphogluconate dehydrogenas), also known as 6PGD, is a 483 amino acid enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in an autosomal dominant fashion. |
Immunogen | Recombinant human PGD (1-483aa) purified from E. coli |
Other Names | 6-phosphogluconate dehydrogenase, Decarboxylating, PGDH, Phosphogluconate dehydrogenase, 6PGD |
Gene, Accession # | NCBI: NP_002622, UniProt: P52209 |
Catalog # | ATGA0419 |
Price | $170, $290 |
Order / More Info | 6-phosphogluconate Dehydrogenase/PGD, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |