Lactate Dehydrogenase A/LDHA, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityLactate Dehydrogenase A/LDHA, Human
CloneAT1A4
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
FormatProtein G purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA, WB, ICC/IF
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DescriptionLactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle.
ImmunogenRecombinant human LDHA (1-332aa) purified from E.coli
Other NamesLactate dehydrogenase A, L-lactate dehydrogenase A chain, Cell proliferation-inducing gene 19 protein, PIG19, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59
Gene, Accession #NCBI: NP_005557, UniProt: P00338
Catalog #ATGA0180
Price$170, $290
Order / More InfoLactate Dehydrogenase A/LDHA, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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