Edit |   |
---|---|
Antigenic Specificity | Wnt-3a, Human |
Clone | 3A6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Wingless-type MMTV integration site family, member 3A (Wnt3a) is a member of the Wnt family. The Wnt gene family is representative of a growing class of multifunctioanl factors that play a role in both tumorigenesis and patterning events required for normal differentiation and development. Wnt3a is a ligand for members of the frizzled family of seven transmembrane receptors. |
Immunogen | Recombinant human Wnt3a (19-352aa) purified from E. coli |
Other Names | Wnt3a, Wingless-type MMTV integration site family, member 3A |
Gene, Accession # | NCBI: NP_149122, UniProt: P56704 |
Catalog # | AWN0924 |
Price | $170, $290 |
Order / More Info | Wnt-3a, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | Chen F, et al. Curcumin increased the differentiation rate of neurons in neural stem cells via wnt signaling in vitro study. (J Surg Res. 2014){https://pubmed.ncbi.nlm.nih.gov/25033705/};;Gong SJ, et al. Upregulation of PP2Ac predicts poor prognosis and contributes to aggressiveness in hepatocellular carcinoma. (Cancer Biol Ther. 2016){https://pubmed.ncbi.nlm.nih.gov/26618405/};;Pan LH, et al. Oncogenic Wnt3a expression as an estimable prognostic marker for hepatocellular carcinoma. (World J Gastroenterol. 2016){https://pubmed.ncbi.nlm.nih.gov/27076768/};;Bai D, et al. Attenuation of Focal Adhesion Kinase Reduces Lipopolysaccharide-Induced Inflammation Injury through Inactivation of the Wnt and NF-κB Pathways in A549 Cells. (Biochemistry (Mosc). 2017){https://pubmed.ncbi.nlm.nih.gov/28371601/};;Meng X, et al. Heterogeneous nuclear ribonucleoprotein A1 interacts with microRNA-34a to promote chondrogenic differentiation of mesenchymal stem cells. (Am J Transl Res. 2017){https://pubmed.ncbi.nlm.nih.gov/28469782/};;Xiang T, et al. Oxidored-nitro domain-containing protein 1 promotes liver fibrosis by activating the Wnt/β-catenin signaling pathway in vitro. (Mol Med Rep. 2017){https://pubmed.ncbi.nlm.nih.gov/28791396/};;Li X, et al. Leptin differentially regulates endochondral ossification in tibial and vertebral epiphyseal plates. Cell Biol Int. 2018{https://pubmed.ncbi.nlm.nih.gov/28980745/};;Xue C, et al. β-Elemene inhibits the proliferation of primary human airway granulation fibroblasts by down-regulating canonical Wnt/β-catenin pathway. (Biosci Rep. 2018){https://pubmed.ncbi.nlm.nih.gov/29358311/};;Wang L, et al. Expression of hepatic Wnt5a and its clinicopathological features in patients with hepatocellular carcinoma. (Hepatobiliary Pancreat Dis Int. 2018){https://pubmed.ncbi.nlm.nih.gov/29709351/};;Liu SQ, et al. Propofol Inhibits Proliferation, Migration, Invasion and Promotes Apoptosis Through Down-Regulating miR-374a in Hepatocarcinoma Cell Lines. (Cell Physiol Biochem. 2018){https://pubmed.ncbi.nlm.nih.gov/30257238/} |