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Antigenic Specificity | Crystallin alpha A/CRYAA, Human |
Clone | c9F2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | alpha-crystallins, a major protein of the ocular lens, are thought to play a role in maintaining lens transparency, which are composed of two gene products alpha-A and alpha-B, for acidic and basic, respectively. alpha-crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP). They act as molecular chaperones and hold unfolded or misfolded proteins in large, water-soluble low molecular weight aggregates. These heterogeneous aggregates consist of 30-40 subunits of the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and the participation in the intracellular architecture. |
Immunogen | Recombinant human Crystallin alpha A (1-173aa) purified from E. coli |
Other Names | Acry-1, Alpha crystallin A chain, CRYA1, CRYAA, Crystallin alpha 1, Crystallin alpha A, Heat shock protein beta 4, HSPB 4, HspB4, Zonular Central Nuclear Cataract |
Gene, Accession # | NCBI: NP_000385, UniProt: P02489 |
Catalog # | ACA0401 |
Price | $170, $290 |
Order / More Info | Crystallin alpha A/CRYAA, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |