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Antigenic Specificity | VTA1, Human |
Clone | AT14G10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB,ICC/IF,FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The VTA1 protein is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. This protein is involved in the sorting and down-regulation of EGFR (By similarity) and involved in HIV-1 budding. |
Immunogen | Recombinant human VTA1 (1-307aa) purified from E. coli |
Other Names | vacuolar protein sorting-associated protein VTA1 homolog, DRG-1, DRG1, LIP5, SBP1 |
Gene, Accession # | NCBI: NP_057569, UniProt: Q9NP79 |
Catalog # | ATGA0403 |
Price | $170, $290 |
Order / More Info | VTA1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |