TDP-43/TARDBP, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityTDP-43/TARDBP, Human
Clonek1B8
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein G purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA, WB, IHC, FACS
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DescriptionTAR DNA binding protein (TARDBP), also known as TDP-43, is a cellular protein. TARDBP was identified as the disease accumulating protein in patients with frontotemporal lobar degeneration (FTLD) with ubiquitin inclusions (FTLD-U) and in amyotrophic lateral sclerosis (ALS). TARDBP functions as a DNA-binding protein and specifically binds to the TAR DNA sequence motifs of HIV. Via this association with TAR motifs, TARDBP acts as a transcriptional repressor and inhibits HIV-1 transcription. In addition, this protein regulates alternate splicing of the cystic fibrosis transmembrane receptor (CFTR) gene.
ImmunogenRecombinant human TARDBP (1-260aa) purified from E. coli
Other NamesTAR DNA binding protein, TDP-43, ALS10, TAR DNA-binding protein 43, TDP43
Gene, Accession #NCBI: NP_031401, UniProt: Q13148
Catalog #ATA0834
Price$170, $290
Order / More InfoTDP-43/TARDBP, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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