Bub3, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityBub3, Human
CloneAT2H6
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
FormatProtein A purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA,WB
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DescriptionBUB3 (budding uninhibited by benzimidazoles 3 homolog) is a conserved component of the mitotic spindle assembly complex (MCC). It contains five WD repeat domains and forms cell cycle constitutive complexes with BUB1 and BUBR1. BUB3 is essential for the kinetochore localization of BUB1 and BUBR1. As a component of the MCC, BUB3 is involved in the essential spindle checkpoint pathway that operates during early embryogenesis. The spindle checkpoint pathway functions to postpone the initiation of anaphase until chromosomes are properly attached to the spindle. This acts to ensure accurate chromosome segregation. In addition, BUB3 plays a role in regulating the establishment of correct kinetochore-microtubule attachments.
ImmunogenRecombinant human BUB3 (1-328aa) purified from E. coli
Other NamesMitotic checkpoint protein BuB3, BuB3L, hBuB3
Gene, Accession #NCBI: NP_004716, UniProt: O43684
Catalog #ATGA0319
Price$170, $290
Order / More InfoBub3, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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