PP2C alpha/PPM1A, Human Antibody from NKMAX Co. Ltd.
Search, find, compare suppliers for anti-PP2C alpha/PPM1A, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PP2C alpha/PPM1A, Human |
| Clone | p6C7 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b kappa |
| Format | Protein A purified |
| Size | 50ul, 100ul |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | ELISA, WB, ICC/IF |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Protein phosphatase 2C (PP2Calpha) is a Mn2+ - or Mg 2+ -dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNk MAPk pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signalingkinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2Calpha, the prototypical member of the PPM family. |
| Immunogen | Recombinant human PP2Calpha/PPM1A (1-382aa) purified from E. coli |
| Other Names | Pyruvate dehydrogenase phosphatase catalytic subunit 1, Pyruvate dehydrogenase acetyl-transferring-phosphatase 1, Protein phosphatase Mg2+/Mn2+dependent 1A, Protein phosphatase 2C, Protein phosphatase 1A (formerly 2C) magnesium-dependent alpha isoform, Protein phosphatase 1A (formerly 2C), PPM2C, PPM1A, PP2CA, PP2C alpha, PDPC 1, PDP 1, PDP, MGC9201, FLJ42306, EC 3.1.3.43 |
| Gene, Accession # | NCBI: NP_066283, UniProt: P35813 |
| Catalog # | ATGA0529 |
| Price | $190, $320 |
| Order / More Info | PP2C alpha/PPM1A, Human Antibody from NKMAX Co. Ltd. |
| Product Specific References | Kim JS, et al. The interaction of hepatitis B virus X protein and protein phosphatase type 2 Calpha and its effect on IL-6. (Biochem Biophys Res Commun. 2006){https://pubmed.ncbi.nlm.nih.gov/17055456/};;Wang K, et al. TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM. (EBioMedicine. 2019){https://pubmed.ncbi.nlm.nih.gov/30926424/};;Wang Z, et al. MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation. (Allergy Asthma Immunol Res. 2020){https://pubmed.ncbi.nlm.nih.gov/32638565/};;Yang J, et al. Knockdown of Mg2+/Mn2+ dependent protein phosphatase 1A promotes apoptosis in BV2 cells infected with Brucella suis strain 2 vaccine. (Exp Ther Med. 2020){https://pubmed.ncbi.nlm.nih.gov/32742335/};;Xia YC, et al. lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p. (Dis Markers. 2021){https://pubmed.ncbi.nlm.nih.gov/34336002/};;Feng D,et al. Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage. (Sci Adv. 2022){https://pubmed.ncbi.nlm.nih.gov/36179025/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
Profile of NKMAX Co. Ltd.