Edit |   |
---|---|
Antigenic Specificity | DKK3, Human |
Clone | AT103B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Dickkopf-related protein 3, also known as DKK3, is a member of the DKK protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. DKK3 is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. |
Immunogen | Recombinant human DKK3 (22-350aa) purified from E. coli |
Other Names | Dickkopf WNT signaling pathway inhibitor 3, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, REIC, RIG, CRRL |
Gene, Accession # | NCBI: NP_001018067, UniProt: Q9UBP4 |
Catalog # | ATGA0476 |
Price | $170, $290 |
Order / More Info | DKK3, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |