MERS-CoV Spike Antibody from NKMAX Co. Ltd.
Search, find, compare suppliers for anti-MERS-CoV Spike antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | MERS-CoV Spike |
| Clone | AT6E6 |
| Host Species | Mouse |
| Reactive Species | MERS-CoV |
| Isotype | IgG1 kappa |
| Format | Protein A purified |
| Size | 50ul, 100ul |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | ELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MERS Spike Antibody (1ug/ml) specifically recognizes MERS Spike and Spike S1 recombinant protein, but not interacted MERS Spike S2 and RBD recombinant protein in ELISA.. MERS-CoV, which causes the Middles East Respiratory Syndrome (MERS), belongs to a family of viruses known as coronaviruses. MERS-CoV was first identified in the Kingdom of Saudi Arabia in 2012, which is a single and positive stranded RNA virus. Dromedary camels are widely considered as the source of the transmission of MERS-CoV. The rate of human transmission among household contacts of MERS patients has been approximately 5 % based on serological analysis. MERS-CoV has four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins. The spike protein, responsible for allowing the virus to attach to and fuse with the membrane of a host cell and is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. MERS-CoV S mediates viral attachment and fusion to human cells via human cellular receptor DPP4, also known as CD26. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
| Immunogen | Recombinant MERS-CoV Spike (18-1296aa) purified from Baculovirus |
| Other Names | Middle East respiratory syndrome coronavirus, Human betacoronavirus 2c EMC/2012, MERS-CoV, MERS, MERSCoV SP, Spike glycoprotein, S glycoprotein, S, Spike protein |
| Gene, Accession # | NCBI: AFS88936, UniProt: K0BRG7 |
| Catalog # | ATGA0598 |
| Price | $170, $290 |
| Order / More Info | MERS-CoV Spike Antibody from NKMAX Co. Ltd. |
| Product Specific References | Lee K, et al. Development of a diagnostic system for detection of specific antibodies and antigens against Middle East respiratory syndrome coronavirus. (Microbiol Immunol. 2018){https://pubmed.ncbi.nlm.nih.gov/30117617/};;Goo J, et al. Characterization of novel monoclonal antibodies against MERS-coronavirus spike protein. (Virus Res. 2020){https://pubmed.ncbi.nlm.nih.gov/31945421/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
Profile of NKMAX Co. Ltd.