NPM1, Human Antibody from NKMAX Co. Ltd.
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| Antigenic Specificity | NPM1, Human |
| Clone | AT23F1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | Protein A purified |
| Size | 50ul, 100ul |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | ELISA,WB,ICC/IF,FACS |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NPM1 is associated with nucleolar ribonucleoprotein structures and bind single-stranded and double-stranded nucleic acids, but it binds preferentially G-Quadruplex forming nucleic acids. It is involved in the biogenesis of ribosomes and may assist small basic proteins in their transport to the nucleolus. Its regulation through SUMOylation (by SENP3 and SENP5) is another facet of the proteins's regulation and cellular functions. It is located in the nucleolus, but it can be translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. The protein is phosphorylated. Chromosomal aberrations involving NPM1 were found in patients with non-Hodgkin lymphoma, acute promyelocytic leukemia, myelodysplastic syndrome, and acute myelogenous leukemia. It has been found in the cytoplasm in patients with primary acute myelogenous leukemia. |
| Immunogen | Recombinant human NPM1(1-294aa) purified from E. coli |
| Other Names | Nucleophosmin, B23, NPM |
| Gene, Accession # | NCBI: NP_002511, UniProt: P06748 |
| Catalog # | ATGA0345 |
| Price | $170, $290 |
| Order / More Info | NPM1, Human Antibody from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
Profile of NKMAX Co. Ltd.