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Antigenic Specificity | CD3 epsilon/CD3E, Human |
Clone | AT3H3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB,ICC/IF,FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multi subunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). It is composed of five invariant polypeptide chains that associate to form three dimers. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |
Immunogen | Recombinant human CD3E (23-126aa) purified from E. coli |
Other Names | T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE |
Gene, Accession # | NCBI: NP_000724, UniProt: P07766 |
Catalog # | ATGA0331 |
Price | $170, $290 |
Order / More Info | CD3 epsilon/CD3E, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |