MYL2, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityMYL2, Human
CloneAT3B2
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
FormatProtein A purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA, WB, ICC/IF, FACS
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DescriptionMyosin, light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy
ImmunogenRecombinant human MYL2 (1-166aa) purified from E. coli
Other NamesSlow cardiac myosin regulatory light chain 2, MLC2, CMH10, DKFZp779C0562, Slow cardiac myosin regulatory light chain 2, MYL2, Slow cardiac myosin regulatory light chain 2 Cardiac myosin light chain-2, MLC 2v, MYL 2, Cardiac ventricular myosin light chain 2, RLC of myosin, Myosin light chain 2 regulatory cardiac slow, Myosin light polypeptide 2 regulatory cardiac slow, Myosin regulatory light chain 2 ventricular cardiac muscle isoform, Myosin regulatory light chain 2 ventricular/cardiac muscle isoform, Regulatory light chain of myosin
Gene, Accession #NCBI: NP_000423, UniProt: P10916
Catalog #ATGA0151
Price$170, $290
Order / More InfoMYL2, Human Antibody from NKMAX Co. Ltd.
Product Specific ReferencesBeveridge RD, et al. The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling. (Cell Cycle. 2014){https://pubmed.ncbi.nlm.nih.gov/25485589/};;Russo V, et al. Porous, Ventricular Extracellular Matrix-Derived Foams as a Platform for Cardiac Cell Culture. (Biores Open Access. 2015){https://pubmed.ncbi.nlm.nih.gov/26487982/};;Mourino-Alvarez L, et al. A comprehensive study of calcific aortic stenosis: from rabbit to human samples. (Dis Model Mech. 2018){https://pubmed.ncbi.nlm.nih.gov/29752279/};;Acharya BR, et al. A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress. (Dev Cell. 2018){https://pubmed.ncbi.nlm.nih.gov/30318244/}
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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