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Antigenic Specificity | MYL2, Human |
Clone | AT3B2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF, FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myosin, light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy |
Immunogen | Recombinant human MYL2 (1-166aa) purified from E. coli |
Other Names | Slow cardiac myosin regulatory light chain 2, MLC2, CMH10, DKFZp779C0562, Slow cardiac myosin regulatory light chain 2, MYL2, Slow cardiac myosin regulatory light chain 2 Cardiac myosin light chain-2, MLC 2v, MYL 2, Cardiac ventricular myosin light chain 2, RLC of myosin, Myosin light chain 2 regulatory cardiac slow, Myosin light polypeptide 2 regulatory cardiac slow, Myosin regulatory light chain 2 ventricular cardiac muscle isoform, Myosin regulatory light chain 2 ventricular/cardiac muscle isoform, Regulatory light chain of myosin |
Gene, Accession # | NCBI: NP_000423, UniProt: P10916 |
Catalog # | ATGA0151 |
Price | $170, $290 |
Order / More Info | MYL2, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | Beveridge RD, et al. The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling. (Cell Cycle. 2014){https://pubmed.ncbi.nlm.nih.gov/25485589/};;Russo V, et al. Porous, Ventricular Extracellular Matrix-Derived Foams as a Platform for Cardiac Cell Culture. (Biores Open Access. 2015){https://pubmed.ncbi.nlm.nih.gov/26487982/};;Mourino-Alvarez L, et al. A comprehensive study of calcific aortic stenosis: from rabbit to human samples. (Dis Model Mech. 2018){https://pubmed.ncbi.nlm.nih.gov/29752279/};;Acharya BR, et al. A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress. (Dev Cell. 2018){https://pubmed.ncbi.nlm.nih.gov/30318244/} |