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Antigenic Specificity | EpCAM/TROP-1, Human |
Clone | AT36F10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Epithelial cell adhesion molecule (EPCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EPCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EPCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EPCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EPCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. |
Immunogen | Recombinant human EpCAM/TROP-1 (24-265aa) purified from E. coli |
Other Names | Epithelial cell adhesion molecules, CD326, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, DIAR5, EGP, GA733 2, HNPCC8 |
Gene, Accession # | NCBI: NP_002345, UniProt: P16422 |
Catalog # | ATGA0515 |
Price | $170, $290 |
Order / More Info | EpCAM/TROP-1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |