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Antigenic Specificity | IRF5, Human |
Clone | 10T1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF, FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interferon regulatory factor 5 (IRF-5) is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs (IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines. |
Immunogen | Recombinant human IRF-5 (176-240aa) purified from E. coli |
Other Names | interferon regulatory factor 5, irf5 |
Gene, Accession # | NCBI: NP_116032.1, UniProt: Q13568 |
Catalog # | ATGA0518 |
Price | $190, $320 |
Order / More Info | IRF5, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | Moen SH, et al. Human Toll-like Receptor 8 (TLR8) Is an Important Sensor of Pyogenic Bacteria, and Is Attenuated by Cell Surface TLR Signaling. (Front Immunol. 2019){https://pubmed.ncbi.nlm.nih.gov/31214180/};;Guo J, et al. A promising role of interferon regulatory factor 5 as an early warning biomarker for the development of human non-small cell lung cancer. (Lung Cancer. 2019){https://pubmed.ncbi.nlm.nih.gov/31447002/} |