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Antigenic Specificity | Beclin 1/BECN1, Human |
Clone | AT45E8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF, FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Beclin-1 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 is a mammalian ortholog of the yeast autophagy-related gene (Atg) 6 and BEC-1 in the C. elegans nematode. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy. |
Immunogen | Recombinant human BECN (1-450aa) purified from E. coli |
Other Names | Beclin 1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, Beclin 1 autophagy related, ATG6, ATG6 autophagy related 6 homolog, VPS30 |
Gene, Accession # | NCBI: NP_003757, UniProt: Q14457 |
Catalog # | ATGA0355 |
Price | $170, $290 |
Order / More Info | Beclin 1/BECN1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |