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Antigenic Specificity | PD-1, Human |
Clone | 4F12 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB,ICC/IF,FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PD-1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PD-1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PD-1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases. |
Immunogen | Recombinant human PDCD1 (21-167aa) purified from E. coli |
Other Names | Programmed cell death 1, CD279, PD1, hPD-1, hPD-l, PDCD1 |
Gene, Accession # | NCBI: AAH74740, UniProt: Q15116 |
Catalog # | APD0811 |
Price | $170, $290 |
Order / More Info | PD-1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |