GIPC1/2, Human Antibody from NKMAX Co. Ltd.
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| Antigenic Specificity | GIPC1/2, Human |
| Clone | AT1G10 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | Protein G purified |
| Size | 50ul, 100ul |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | ELISA, WB, FACS |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GIPC, GAIP interacting protein at the C terminus, is a PDZ domain containing protein that interacts with RGS-GAIP. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain. |
| Immunogen | Recombinant human GIPC2 (1-315aa) purified from E. coli |
| Other Names | PDZ domain containing family member 2, SEMCAP2 |
| Gene, Accession # | NCBI: NP_060125.4, UniProt: Q8TF65 |
| Catalog # | ATGA0223 |
| Price | $170, $290 |
| Order / More Info | GIPC1/2, Human Antibody from NKMAX Co. Ltd. |
| Product Specific References | Wang Q, et al. Modulation of m-Opioid Receptor Signaling by RGS19 in SH-SY5Y Cells. (Mol Pharmacol. 2013){https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558815/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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