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Antigenic Specificity | CMBL, Human |
Clone | AT2B11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CMBL (carboxymethylenebutenolidase homolog) is a 245 amino acid cytosolic protein and cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL is the human homolog of Pseudomonas dienelactone hydrolase, a protein that participates in the bacterial halocatechol degradation pathway. That is ubiquitously expressed with high expression in liver, colon, kidney and small intestine, where it acts as a bioactivating enzyme for a prodrug type angiotensin II type 1 receptor antagonist known as olmesartan medoxomil. CMBL is inhibited by p-chloromercuribenzoate (PCMB). |
Immunogen | Recombinant human CMBL (1-245aa) purified from E. coli |
Other Names | Carboxymethylenebutenolidase homolog |
Gene, Accession # | NCBI: NP_620164, UniProt: Q96DG6 |
Catalog # | ATGA0233 |
Price | $170, $290 |
Order / More Info | CMBL, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |