ASF1B, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityASF1B, Human
CloneAT1D4
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
FormatProtein A purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA,WB
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DescriptionASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. Delivering histone H3/H4 dimers to CAF-1 or HIRA histone deposition complexes to facilitate replication-coupled and replication-independent nucleosome assembly on DNA. Both ASF1A and ASF1B are phosphorylated in S phase by the Tousled-like kinases TLK1 and TLK2, and are dephosphorylated when TLK1 and TLK2 are inactivated by Chk1 kinase in response to replicative stress.
ImmunogenRecombinant human ASF1B (1-202aa) purified from E. coli
Other NamesASF1 anti-silencing function 1 homolog B (S.cerevisiae), CIA-II
Gene, Accession #NCBI: NP_060624, UniProt: Q9NVP2
Catalog #ATGA0315
Price$170, $290
Order / More InfoASF1B, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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