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Antigenic Specificity | MyD88, Human |
Clone | AT22F11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB,ICC/IF,FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myeloid differentiation primary response gene 88 (MYD88) is adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. |
Immunogen | Recombinant human MYD88 (1-309aa) purified from E. coli |
Other Names | Myeloid differentiation primary response protein MyD88, MYD88D |
Gene, Accession # | NCBI: NP_002459, UniProt: Q99836 |
Catalog # | ATGA0247 |
Price | $170, $290 |
Order / More Info | MyD88, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |