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Antigenic Specificity | Calcineurin A/PPP3CA, Human |
Clone | AT1E11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PPP3CA, also known as Calcineurin A, is a major soluble calmodulin binding protein in the brain, a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively narrow substrate specificity. It activates the T cells of the immune system and can be blocked by drugs. PPP3CA activates NFATc, a transcription factor by dephosphorylating it. The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2. |
Immunogen | Recombinant human PPP3CA (1-511aa) purified from E. coli |
Other Names | Protein phosphatase 3 catalytic subunit alpha, CAM-PRP catalytic subunit, Calcineurin A alpha, Calmodulin-dependent calcineurin A subunit alpha isoform, CNA alpha, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CALNA, CALN, CNA, CNA1, PPP2B |
Gene, Accession # | NCBI: NP_001124163, UniProt: Q08209 |
Catalog # | ATGA0505 |
Price | $170, $290 |
Order / More Info | Calcineurin A/PPP3CA, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |