NBL1, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityNBL1, Human
CloneAT38G8
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein A purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA, WB, ICC/IF, FACS
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DescriptionNBL1 is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development and alternatively spliced transcript variants have been identified for this gene. Also, as a tumor suppressor gene of neuroblastoma may play an important role in preventing cells from entering the final stage (G1/S) of the transformation process. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 have been observed.
ImmunogenRecombinant human NBL1 (18-181aa) purified from E. coli
Other NamesNeuroblastoma suppressor of tumorigenicity 1, D1S1733E, DAN, DAND1, NB, NO3
Gene, Accession #NCBI: NP_005371, UniProt: P41271
Catalog #ATGA0267
Price$170, $290
Order / More InfoNBL1, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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