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Antigenic Specificity | LSM5, Human |
Clone | AT25F8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB,ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LSM5, also known as YER146W, is a 91 amino acid protein belonging to the snRNP Sm family. Localized to the nucleus, LSm5 has been found to play a role in the formation and function of the U6 snRNP. Specifically, LSm5 binds to the 3' end of U6 snRNA and facilitates U4/U6 duplex formation. Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. |
Immunogen | Recombinant human LSM5 (1-91aa) purified from E. coli |
Other Names | u6 snRNA-associated Sm-like protein LSm5 isoform a, LSM5 homolog, u6 small nuclear RNA associated (S.cerevisiae), YER146W |
Gene, Accession # | NCBI: NP_036454, UniProt: Q9Y4Y9 |
Catalog # | ATGA0385 |
Price | $170, $290 |
Order / More Info | LSM5, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |