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Antigenic Specificity | TIP30/HTATIP2, Human |
Clone | AT5D6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. |
Immunogen | Recombinant human HTATIP2 (1-242aa) purified from E. coli |
Other Names | Oxidoreductase HTATP2, CC3, TIP30, SDR44u1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30 |
Gene, Accession # | NCBI: AAH15358, UniProt: Q9BUP3 |
Catalog # | ATGA0444 |
Price | $170, $290 |
Order / More Info | TIP30/HTATIP2, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |