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Antigenic Specificity | NKp46/NCR1, Human |
Clone | n1D9 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel Nk cell-specific molecule involved in human Nk cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appearto be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in Nk cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. |
Immunogen | Recombinant human Nkp46/NCR1 (22-255aa) purified from E. coli. |
Other Names | NKp46 Extracellular Ig-like domain, NK-p46, NK cell-activating receptor, NCR1, NCR, Natural killer cell p46-related protein, Natural cytotoxicity triggering receptor 1 isoform a, Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, Ly96, LY94, hNKp46, CD335 antigen |
Gene, Accession # | NCBI: NP_004820, UniProt: O76036 |
Catalog # | ATGA0526 |
Price | $190, $320 |
Order / More Info | NKp46/NCR1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |