Description | Rac is a subfamily of the Rho family of GTPases, small (~21 kDa) signaling G proteins (more specifically a GTPase). When bound to GTP, Rac is activated. In its activated state, Rac participates in the regulation of cell movement, through its involvement in structural changes to the actin Cytoskeleton. Rac is small GTPases that have been linked to multiple human cancers and are implicated in epithelial to mesenchymal transition, cell-cycle progression,migration/invasion, tumor growth, angiogenesis, and oncogenic transformation. |
Other Names | as-related C3 botulinum toxin substrate 3, Cell migration-inducing gene 5 protein, EN-7, Gx, HSPC022, MIG 5, MIG5, Migration inducing gene 5, Migration inducing protein 5, p21 Rac1, p21 Rac2, p21 Rac3, RAC1, Rac1B, RAC2, RAC3, Ras like protein TC25, Ras related C3 botulinum substrate 1, Ras related C3 botulinum substrate 2, Ras related C3 botulinum substrate 3, Ras related C3 botulinum toxin substrate 1, Ras related C3 botulinum toxin substrate 1 isoform Rac1, Ras related C3 botulinum toxin substrate 1 isoform Rac1 MGC111543, Ras related C3 botulinum toxin substrate 2, Ras related C3 botulinum toxin substrate 3, Rho family small GTP binding protein Rac1, Rho family small GTP binding protein Rac2, Rho family small GTP binding protein Rac3, RP23-84C12.18, Small G protein, TC 25 |