BAK, Human Antibody from NKMAX Co. Ltd.
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| Antigenic Specificity | BAK, Human |
| Clone | AT38E2 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a kappa |
| Format | purified |
| Size | 50ul, 100ul |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | ELISA, WB, ICC/IF, FACS |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BAK1 encodes an receptor-like kinase (RLK) with a putative extracellular domain, a single transmembrane domain, an intracellular-juxtamembrane domain, and a kinase domain. BAK1 expression is associated with the progression of Prostate cancer (CaP). BAK1 appears to function in distinct receptor-signaling complexes to integrate multiple microbe-associated molecular pattern (MAMP) perception into downstream-signaling events. BAK1 can serve multiple purposes to simultaneously modulate MAMP-receptor complexes, BR signaling, and cell death for the benefit of bacterial infection, life style, and fitness. |
| Immunogen | Recombinant human BAK (29-187aa) purified from E.coli |
| Other Names | BCL2-antagonist/killer 1, Apoptosis regulator BAK, BAK, BAK-LIKE, Bcl-2 homologous antagonist/killer, Bcl2-L-7, BAK-1, BAK 1, BAK like, Bak NT, BAK1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl2 homologous antagonist killer, Bcl2 like 7 Protein, BCL2-antagonist/killer 1, BCL2L7, CDN 1, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK |
| Gene, Accession # | NCBI: NP_001179, UniProt: Q16611 |
| Catalog # | ATGA0523 |
| Price | $190, $320 |
| Order / More Info | BAK, Human Antibody from NKMAX Co. Ltd. |
| Product Specific References | Singh A, et al. Podophyllotoxin and Rutin Modulates Ionizing Radiation-Induced Oxidative Stress and Apoptotic Cell Death in Mice Bone Marrow and Spleen. (Front Immunol. 2017){https://pubmed.ncbi.nlm.nih.gov/28289414/};;Mebratu YA, et al. Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria. (Nat Commun. 2017){https://pubmed.ncbi.nlm.nih.gov/28986568/};;Liu P, et al. Downregulation of microRNA-125a is involved in intervertebral disc degeneration by targeting pro-apoptotic Bcl-2 antagonist killer 1. (Iran J Basic Med Sci. 2017){https://pubmed.ncbi.nlm.nih.gov/29299204/};;Loo LSW, et al. BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells. (Cell Death Dis. 2020){https://pubmed.ncbi.nlm.nih.gov/32424151/};;Shen J, et al. TLR9 regulates NLRP3 inflammasome activation via the NF-kB signaling pathway in diabetic nephropathy. (Diabetol Metab Syndr. 2022){https://pubmed.ncbi.nlm.nih.gov/35120573/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
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