Thymidylate synthase/TYMS, Human Antibody from NKMAX Co. Ltd.
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| Antigenic Specificity | Thymidylate synthase/TYMS, Human |
| Clone | AT21S5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b kappa |
| Format | Protein G purified |
| Size | 50ul, 100ul |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | ELISA, WB, ICC/IF, FACS |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dMTP) is an essential step for the formation of thymine nucleotides. This process is catalyzed by thymidylate synthase (TS or TYMS). TYMS is an intracellular enzyme that provides the sole de novo source of thymidylate in activity highest proliferating cells. Being the exclusive source of dTMP, TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head and neck. TS expression may be useful in predicting overall patient survival, but the prognostic value of TS expression continues to be a subject of investigation for different types of cancers. |
| Immunogen | Recombinant TYMS (1-313aa) purified from E. coli |
| Other Names | HST422, TMS, TS, d TMP synthase, EC 2.1.1.45, MGC88736, Thymidylate synthase, Thymidylate synthetase, Tsase, TYMS, TYMS protein, Tyms thymidylate synthetase |
| Gene, Accession # | NCBI: NP_001062, UniProt: P04818 |
| Catalog # | ATGA0169 |
| Price | $170, $290 |
| Order / More Info | Thymidylate synthase/TYMS, Human Antibody from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
Profile of NKMAX Co. Ltd.