GCLM, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityGCLM, Human
CloneAT2D12
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein G purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA,WB,ICC/IF
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DescriptionGCLM (Glutamate-cysteine ligase, modifier subunit), also known as gamma-glutamylcysteine synthetase, is first rate limiting enzyme of glutathione synthesis. GCLM is heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. GCLM deficiency has been implicated in some forms of hemolytic anemia. Also, GCLM is a molecular target for amelioration of cisplatin restance in lung cancer.
ImmunogenRecombinant human GCLM (1-274aa) purified from E. coli
Other NamesGlutamate-cysteine ligase modifier subunit, Glutamate-cysteine ligase, modifier subunit, GLCLR
Gene, Accession #NCBI: NP_002052, UniProt: P48507
Catalog #ATGA0229
Price$170, $290
Order / More InfoGCLM, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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