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Antigenic Specificity | Carbonyl reductase 1/CBR1, Human |
Clone | AT4E12 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Carbonyl reductase 1 (CBR1) is a NADPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogenases/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E). |
Immunogen | Recombinant human CBR1 (1-277 aa ) purified from E. coli |
Other Names | Carbonyl reductase 1, Carbonyl reductase 1, CBR, hCBR1, SDR21C1, CBR1, Carbonyl reductase 1 15 hydroxyprostaglandin dehydrogenase [NADP+], Carbonyl reductase [NADPH] 1.CBR 1, CRN, NADPH dependent carbonyl reductase 1, Prostaglandin 9 ketoreductase, Prostaglandin E(2) 9 reductase. |
Gene, Accession # | NCBI: NP_001748, UniProt: P16152 |
Catalog # | ATGA0200 |
Price | $170, $290 |
Order / More Info | Carbonyl reductase 1/CBR1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |