NQO2, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityNQO2, Human
CloneAT1E3
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein G purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA, WB, ICC/IF
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DescriptionQuinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates. NQO2 is inhibited by flavones such as quercetin. Also benzo (a) pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates. The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm.
ImmunogenRecombinant human NQO2 (1-231aa) purified from E. coli
Other NamesN-ribosyldihydronicotinamide:quinone reductase 2, NMOR2, NAD(P)H menadione oxidoreductase 2, Dioxin-inducible, NAD(P)H quinone dehydrogenase 2, Quinone reductase 2, QR2, DHQV, DIA6, NRH:quinone oxidoreductase 2
Gene, Accession #NCBI: AAH06096, UniProt: P16083
Catalog #ATGA0192
Price$170, $290
Order / More InfoNQO2, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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