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Antigenic Specificity | NQO2, Human |
Clone | AT1E3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates. NQO2 is inhibited by flavones such as quercetin. Also benzo (a) pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates. The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm. |
Immunogen | Recombinant human NQO2 (1-231aa) purified from E. coli |
Other Names | N-ribosyldihydronicotinamide:quinone reductase 2, NMOR2, NAD(P)H menadione oxidoreductase 2, Dioxin-inducible, NAD(P)H quinone dehydrogenase 2, Quinone reductase 2, QR2, DHQV, DIA6, NRH:quinone oxidoreductase 2 |
Gene, Accession # | NCBI: AAH06096, UniProt: P16083 |
Catalog # | ATGA0192 |
Price | $170, $290 |
Order / More Info | NQO2, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |